Sean Payton returned to the Superdome for the first time as the head coach of the Denver Broncos, facing his former team, the New Orleans Saints. The occasion was made even more special as the Saints honored Drew Brees, their all-time quarterback. Payton's Broncos secured a decisive 33-10 victory, marking their best start since 2016.

The Broncos showcased a dominant performance, with a strong defense that recorded six sacks and a defensive touchdown. Offensively, they rushed for 225 yards, led by Javonte Williams and quarterback Bo Nix.