The Green Bay Packers decisively defeated the San Francisco 49ers, winning 38-10 despite the 49ers missing eight starters, including key players like Brock Purdy and Nick Bosa. The Packers established an early lead, scoring 10 points in the first quarter and extending their advantage to 28 points at one point.

Rashan Gary and Xavier McKinney were standout performers, with Gary contributing a sack and McKinney securing an interception that led to a touchdown. Josh Jacobs also had a significant impact, rushing for over 100 yards and scoring a touchdown. The win improved the Packers' record to 8-3 as they look ahead to their Thanksgiving Day game.