In a significant blow to the San Francisco 49ers, left tackle Trent Williams will miss Sunday’s game against the Green Bay Packers due to an ankle injury, forcing Jaylon Moore to step in as the starter. This matchup marks the first start for quarterback Brandon Allen since the 2021 season, as Brock Purdy is sidelined with a shoulder issue.

Additionally, the 49ers will be without key players including Nick Bosa and Charvarius Ward, while the Packers are also dealing with injuries to Jaire Alexander and Edgerrin Cooper.

The Houston Texans face a challenging matchup against the Green Bay Packers, particularly with several key players sidelined for the Texans. Notably, linebacker Azeez Al-Shaair and rookie cornerback Kamari Lassiter are among the inactives, which could significantly impact the Texans' defensive strategy.

On the Packers' side, former first-round pick Devonte Wyatt will also miss the game due to an ankle injury. Despite these setbacks, the game will kick off at 12 noon CT on CBS and Paramount+.