The Buffalo Bills are looking to rebound from their recent loss to the Baltimore Ravens as they prepare to face the Houston Texans, who lead the AFC South. With a strong record of 18-5 following losses under head coach Sean McDermott, the Bills aim to regain their momentum.

This matchup also highlights the storyline of Stefon Diggs, who was traded from Buffalo to Houston, alongside former Bills players Tim Settle, Jerry Hughes, and Robert Woods.

Quarterbacks Josh Allen and C.J. Stroud are both in the running for NFL MVP, making this game crucial for playoff seeding as both teams hold 3-1 records. Defensive-minded coaches Sean McDermott and DeMeco Ryans will also be in focus as they lead their respective teams.