The Houston Texans are set to face the Tennessee Titans in Week 18, having already secured the AFC South title and home-field advantage for the playoffs. With nothing on the line for either team, the Texans are in a position to consider resting their starters. However, head coach DeMeco Ryans has indicated that most starters will play, despite some key injuries, including Denico Autry, Foley Fatukasi, Shaq Mason, and Jeff Okudah, who have been ruled out for the game.

Quarterback C.J. Stroud, who is not on the injury report, is expected to start, although he may not play the entire game. Other offensive starters like Joe Mixon, Nico Collins, Robert Woods, and John Metchie III are also anticipated to take the field. On defense, Will Anderson Jr. and Danielle Hunter will lead the charge, while Derek Stingley Jr. and Calen Bullock will be key in the secondary. The Texans are looking to finish the regular season strong, aiming for a 10-win record.