The Indianapolis Colts are facing injury challenges as they prepare for their game against the New England Patriots. Key players such as wide receivers Josh Downs and Ashton Dulin will miss the matchup, while Alec Pierce's participation remains uncertain.

Despite these setbacks, Michael Pittman Jr. is set to play after recovering from a back injury. The Colts will also rely on rookie AD Mitchell to step up in the slot. The game is scheduled for Sunday at Gillette Stadium.