The Indianapolis Colts have made significant changes to their safety lineup, placing Trevor Denbow on injured reserve due to a knee injury sustained in the recent game against the Texans.

In response, the team has signed Ronnie Harrison Jr. to the active roster. Denbow has been a key contributor on special teams, while Harrison has seen limited action this season.

Furthermore, the Colts have added offensive tackle Sebastian Gutierrez and guard Josh Sills to their practice squad, releasing Jack Wilson to accommodate these moves.