Kadarius Toney and Caleb Farley, both 2021 first-round NFL draft picks, were cut as teams reduced rosters to 53 players. Toney faced injuries and inconsistency after playing a key role in the Chiefs' Super Bowl win.

Farley's career has also been hampered by injuries, and he missed the entire previous season due to personal loss.

Other notable roster changes include JuJu Smith-Schuster's release from the Chiefs, CeeDee Lamb's contract extension with the Cowboys, and ongoing recovery for players like Nick Chubb and T.J. Hockenson.