The Kansas City Chiefs are set to welcome back running back Isiah Pacheco, who has been on injured reserve since a fibula fracture in Week 2. Head coach Andy Reid confirmed that both Pacheco and pass-rusher Charles Omenihu will begin practicing, although neither is expected to play against the Buffalo Bills this week.

Pacheco has been crucial to the Chiefs' success, contributing significantly to their two recent Super Bowl victories and leading the NFL in rushing yards during last year's playoffs. His absence has been felt, but the Chiefs have managed with Kareem Hunt stepping up as the leading rusher this season.

This upcoming game against the Bills is pivotal, as a victory would position the Chiefs alongside the 1990 49ers as the only teams to start a season 10-0 after winning back-to-back championships.