The Chargers faced the Kansas City Chiefs in a tough 17-10 loss, showcasing the struggles of quarterback Justin Herbert amidst injury woes. Herbert, playing with a brace on his injured ankle, lacked support from key offensive players and was constantly pressured throughout the game.

Despite a promising start, the Chargers' performance was hindered by injuries to several key players, including Joey Bosa and Rashawn Slater. Coach Jim Harbaugh expressed frustration over pre-snap penalties and missed opportunities, leaving the Chargers at a 2-2 record.