The Los Angeles Rams are riding a two-game winning streak and have surpassed the .500 mark for the first time this season, with playoff aspirations on the horizon.

Quarterback Matthew Stafford delivered a stellar performance against the Buffalo Bills, throwing for 320 yards and two touchdowns. Meanwhile, the San Francisco 49ers, fresh off a victory over the Chicago Bears, pose a significant challenge ahead.

Key injuries could impact both teams, with the Rams missing cornerback Cobie Durant and the 49ers potentially without star defensive end Nick Bosa. The upcoming matchup is set to be a crucial NFC West clash.