The Miami Dolphins are set to face the San Francisco 49ers in a crucial Week 16 matchup, both teams holding a 6-8 record and clinging to slim playoff hopes.

With injuries affecting both rosters, the Dolphins will be without long snapper Blake Ferguson and have several key players listed as questionable, including wide receiver Tyreek Hill. The 49ers also face significant injury challenges, particularly in their running back corps.

Historically, the Dolphins lead the regular season series against the 49ers, but both teams are struggling to meet expectations this season. The game is expected to be a defensive battle, with Miami hoping to capitalize on San Francisco's recent poor performance.