The Los Angeles Rams are currently tied for last in the NFC West but have a crucial opportunity to improve their standing against the struggling New England Patriots.
Meanwhile, the Arizona Cardinals are on a four-game win streak and will use their bye week to prepare for a pivotal matchup against the Seattle Seahawks, who are facing a must-win situation against the San Francisco 49ers.
The 49ers, gaining momentum with the return of All-Pro rusher Christian McCaffrey, are poised to challenge for the division lead.