The San Francisco 49ers are struggling with a 2-3 start, raising concerns about their performance without star running back Christian McCaffrey. The team has faced significant injuries, impacting their ability to finish games, as evidenced by multiple blown leads against division rivals.

Despite quarterback Brock Purdy's decent stats, the absence of McCaffrey is evident in their red zone struggles and overall offensive efficiency. The 49ers have a history of slow starts but have often rallied in the second half of the season.