San Francisco 49ers running back Isaac Guerendo is optimistic about playing in the upcoming Thursday Night Football game against the Los Angeles Rams, despite dealing with a sprained foot. Sources indicate that he feels good and is listed as questionable for the match.
If Guerendo cannot play, Patrick Taylor is expected to take over the running back duties, given his familiarity with the team. Israel Abanikanda is also in the mix but may not be a starting option if Guerendo is available.