In a commanding performance, Josh Jacobs led the Green Bay Packers to a 38-10 victory over the San Francisco 49ers, rushing for 106 yards and scoring three touchdowns, tying his career high. This game marked a significant moment as it was the first instance in 55 games that a player rushed for over 100 yards against the 49ers.

The 49ers, missing key players due to injuries, struggled to keep pace, with Brandon Allen stepping in at quarterback. The Packers capitalized early, scoring on their first three possessions and maintaining control throughout the game.