This article highlights key fantasy football waiver wire pickups for Week 11, focusing on several running backs and a wide receiver.

Isaac Guerendo of the San Francisco 49ers has struggled to find playing time since the return of Christian McCaffrey, making him a player to avoid. Meanwhile, MarShawn Lloyd, Zach Charbonnet, Tyjae Spears, Alexander Mattison, and Cedric Tillman are recommended for addition in various league formats due to their potential impact.