James Cook is highlighted as a preferable option for Daily Fantasy Sports lineups over Joe Mixon, given his stronger performance this season and the advantage of playing behind a more effective offensive line. With 19 total touchdowns this season, including both regular season and playoffs, Cook is expected to have a better outing against the Chiefs compared to Mixon, who faces a tough run defense and has struggled with production recently.

James Cook has struggled to find consistent usage, failing to log double-digit carries in three of his 17 games this season. In a previous matchup against the Ravens, he caught only one pass, and with Baltimore's dominant run defense limiting running backs to 3.45 yards per carry and just eight rushing touchdowns, Cook's role is expected to diminish further. As the Bills aim to advance, the focus will likely shift to maximizing Josh Allen's contributions, making Cook a low-usage risk for fantasy lineups.

James Cook has been a standout performer for Buffalo, rushing for 120 yards and a touchdown against Denver in the Wild Card round. He has been particularly effective in recent games, recording six touchdowns in the last five outings and totaling 18 for the season, showcasing his growing importance in the Bills' offensive scheme.

James Cook has emerged as a notable running back option for DFS contests during the Divisional Round. He has shown potential in recent games, making him an interesting target for fantasy managers looking to optimize their lineups. His performance will be crucial as the team advances in the playoffs, and his ability to contribute effectively could play a significant role in their success.

James Cook is a key player for the Bills as they advance to the Divisional Round. After a strong performance in the Wild Card round, he presents an intriguing option for DFS contests. His ability to contribute significantly in the playoffs could make him a valuable asset as the Bills face tough competition ahead.