Purdue has 14 alumni on NFL rosters for the 2025 season, led by George Karlaftis in Kansas City. Aidan O’Connell and Raheem Mostert link up for the Raiders, while Tyrone Tracy Jr. and Marcus Mbow may pair again with the Giants. Charlie Jones, Payne Durham, Derrick Barnes, Sanoussi Kane, Rondale Moore, David Bell, Cory Trice Jr., Jalen Graham, and Reese Taylor are scattered across the league, offering depth and late-round fantasy/IDP upside across Bengals, Buccaneers, Lions, Ravens, Vikings, Browns, Steelers, 49ers, Giants, and Broncos.

The Purdue pipeline continues to influence dynasty and streamer decisions, with injury notes, camp chatter, and depth-chart shifts shaping how owners value Purdue-affiliated players in the weeks ahead. Stakeholders should monitor IR statuses for O’Connell, backfield splits in Vegas, and Giants’ backfield competition as the season unfolds.

Kansas City faces a near-term holdout on Trent McDuffie, with no multiyear deal expected before the season opens against the Chargers. McDuffie, coming off career-best metrics (two INTs, 13 pass breakups, 59 tackles) and a league-high 996 defensive snaps near the line, is a priority but talks have stretched into Week 1. KC may opt for dialogue into 2024 and, if unresolved, could tag him in 2027. Sauce Gardner’s extension benchmark looms as a price reference for McDuffie.

The 2022 class—Karlaftis, Pacheco, Cook, Chenal, Watson—helped cement KC’s dynasty, which has already claimed back-to-back titles and reached the title game in three straight seasons. The Jets’ Gardner deal and Tyreek Hill’s trade backdrop shape the market for top corners and star defenders as KC manages cap and roster longevity ahead of a pivotal season opener vs. LA.

George Karlaftis leans into Brazilian jiu-jitsu to sharpen leverage and hand-fighting for the Chiefs’ pass rush. As a blue belt training under Master Dave Smarr, he pairs 6 a.m. sessions with Tamba Hali and Joe Kim to translate grappling into edge-rush technique.

He signed a four-year, $93 million extension after leading KC with eight sacks in 2024, and his unit is framed alongside Trent McDuffie, Isiah Pacheco and Bryan Cook as a college of players chasing another deep playoff run with cross‑training potentially boosting fantasy upside.