Detroit faces Kansas City in primetime with multiple injuries thinning the Lions’ toolkit. Five Lions players must elevate their games: Amik Robertson handles outside coverage with Arnold and D.J. Reed sidelined; Rock Ya-Sin steps into Arnold’s outside/slot role; Dan Skipper protects Goff against George Karlaftis, while Isaac TeSlaa and Kalif Raymond contend for snaps in the receiving corps. Jahmyr Gibbs provides the offense with a dual threat to slow KC’s relentless pass rush and pace the game.

KC’s offense remains a test with Mahomes orchestrating the aerial attack and Karlaftis pressuring the QB. The Lions must leverage tempo and efficient ball movement to keep the shootout at bay, lean on Skipper’s protection, and exploit Gibbs’ versatility to control pace. If Detroit sustains long drives and Gibbs echoes recent production, the rematch could widen Detroit’s streak to five.

Charles Omenihu's ankle issue remains on the radar for Week 6 against Detroit, but he practiced fully and played in Week 5 vs Jacksonville, keeping him in the mix for Sunday Night Football. If he can go, KC's defensive line should stay intact; if not, George Karlaftis, Malik Herring, and Ashton Gillotte step into larger roles to pressure Jared Goff in a prime-time test.

Fantasy takeaway: monitor Omenihu's status leading up to kickoff. A healthy game limits downside for KC’s front, while an absence would lift the ceiling for Karlaftis and the depth trio in deeper rosters or DFS tournaments, especially if the Lions' protection holds up under extra pressure.