In dynasty fantasy football, knowing which players to buy is crucial, but understanding when to sell is equally vital. Holding on to players who are declining can lead to significant losses. For example, Anthony Richardson, quarterback for the Indianapolis Colts, has struggled this season with injuries and poor performance, making him a candidate to sell before his value plummets. Similarly, Isiah Pacheco of the Kansas City Chiefs faced a serious injury and has not regained his position as the lead back, indicating a need for dynasty managers to consider trading him. Tua Tagovailoa, despite prior potential, continues to grapple with concussion issues, diminishing his long-term viability. Keon Coleman of the Buffalo Bills has had a disappointing rookie year, while Travis Etienne Jr. has experienced back-to-back subpar seasons. Each player's situation highlights the importance of proactive decision-making in fantasy football leagues.