San Francisco's All-Pro running back Christian McCaffrey will be sidelined for the season opener against the New York Jets due to a persistent calf and Achilles tendon injury. Despite returning to practice briefly, he was unexpectedly ruled out before the game.

In McCaffrey's absence, Jordan Mason is set to carry the workload at running back. Meanwhile, Trent Williams has been activated after a contract holdout, bolstering the offensive line. The Jets have also made roster adjustments, including signing new players and placing linebacker Zaire Barnes on injured reserve.

Christian McCaffrey, the San Francisco All-Pro running back, missed the season opener against the New York Jets due to a lingering calf and Achilles issue.

Despite being listed as questionable, he was a late scratch, resulting in Jordan Mason stepping up with an impressive performance of 147 yards rushing and a touchdown in San Francisco's victory.

The team adapted well, showcasing their depth and commitment to the running game even in McCaffrey's absence.

The Jets finalized their 53-man roster after making 37 moves on Tuesday. Rookie quarterback Jordan Travis remains on the non-football injury list, while only Tyrod Taylor stands behind Aaron Rodgers at the position.

Injuries have also affected the roster, with Leki Foto and Kenny Yeboah placed on injured reserve but eligible to return. Multiple players were waived, including defensive backs, offensive linemen, linebackers, tight ends, wide receivers, defensive linemen, running backs, and a kicker.