San Francisco's All-Pro running back Christian McCaffrey will be sidelined for the season opener against the New York Jets due to a persistent calf and Achilles tendon injury. Despite returning to practice briefly, he was unexpectedly ruled out before the game.

In McCaffrey's absence, Jordan Mason is set to carry the workload at running back. Meanwhile, Trent Williams has been activated after a contract holdout, bolstering the offensive line. The Jets have also made roster adjustments, including signing new players and placing linebacker Zaire Barnes on injured reserve.

Aaron Rodgers' return takes center stage as the New York Jets face the San Francisco 49ers in a critical matchup at Levi’s Stadium.

The 49ers grapple with key injuries, particularly concerning Christian McCaffrey, while the Jets are banking on Rodgers to help them build a competitive presence in the AFC.

With both teams entering the season with different hurdles to overcome, anticipation builds for an exciting encounter in Week 1.

The San Francisco 49ers face the New York Jets in their season opener, but injuries could significantly affect their lineup. Safety Talanoa Hufanga is doubtful due to a knee injury, while running back Christian McCaffrey and left guard Aaron Banks are both questionable.

Defensive end Yetur Gross-Matos and linebacker Dee Winters have been ruled out. The 49ers may elevate practice squad players to fill gaps in their lineup, particularly with injuries impacting their defense.

Linebacker Haason Reddick will not participate in the New York Jets' season opener due to a contract dispute. Coach Robert Saleh confirmed Reddick's absence, noting that he hasn't reported to the team since his trade from Philadelphia was finalized.

Reddick, a two-time Pro Bowl player who has upheld a high level of performance, is seeking a contract extension and has requested a trade from the Jets, a move rejected by general manager Joe Douglas.

Haason Reddick is set to miss the New York Jets' season opener against the San Francisco 49ers as he continues a contract dispute with the team, having not been present at the facility since his trade from Philadelphia.

Coach Robert Saleh acknowledged Reddick's situation and emphasized the team's support when he returns, despite Reddick's ongoing holdout which has already led to significant fines.