Many fantasy managers might be hesitant to draft running backs coming off poor seasons, but targeting players like Christian McCaffrey, Travis Etienne Jr., and Kenneth Walker III could pay off significantly in best ball formats. McCaffrey, despite an injury-riddled 2024 season with the San Francisco 49ers, showed glimpses of his elite potential and has a proven track record as a top fantasy performer. Meanwhile, Etienne's struggles with hamstring issues hindered his previous season's performance with the Jacksonville Jaguars, but a new offensive scheme could rejuvenate his game. Walker, gaining a new offensive coordinator in 2025, could also see a rise in productivity. These players present an opportunity for savvy fantasy managers to capitalize on their perceived lower value and reap the rewards in upcoming drafts.