Marquise Blair's career has faced significant setbacks due to injuries, including a torn ACL in 2020 and a fractured kneecap in 2021, which limited his playing time. After being released by the Seahawks and having a brief stint with the Panthers, he didn't play at all last season due to an Achilles injury. However, Blair has made a successful comeback, impressing the Seahawks in workouts and during preseason games, where he recorded nine tackles, a quarterback pressure, and a pass breakup. Although he didn't make the initial roster, his performance earned him a spot on the practice squad, providing depth at strong safety and a chance to impact special teams as starters return from injury.