Deebo Samuel, a prominent wide receiver for the San Francisco 49ers, is facing a calf strain that is expected to sideline him for several weeks. This injury comes at a challenging time for the team, which is already dealing with absences from Christian McCaffrey and George Kittle.

With Samuel's condition being monitored, he has not practiced since his injury was reported, and a return could be expected by Week 6 or 7. Samuel's historical performance makes him an essential player in fantasy football, but managers will need to find a temporary replacement until he recuperates.