The San Francisco 49ers face a challenging situation as wide receiver Brandon Aiyuk is likely out for the season due to a suspected ACL injury sustained during their recent loss to the Kansas City Chiefs.

Coach Kyle Shanahan expressed concern over Aiyuk's condition, which adds pressure to an already depleted receiving corps. Deebo Samuel, who was ill and unable to finish the game, and Jauan Jennings, dealing with a hip injury, further complicate the team's offensive strategy.

With Aiyuk sidelined, rookies Ricky Pearsall and Jacob Cowing stepped up, showcasing their potential to fill the void left by the injured stars. The 49ers may need to explore external options if injuries continue to plague their roster as the trade deadline approaches.