With Super Bowl LIX now a memory, teams are starting to pivot towards the offseason, particularly focusing on pivotal players heading into free agency. Tee Higgins stands out as a major needle-mover for fantasy football, with potential destinations including the Patriots and Chargers. His move could elevate whoever's under center for that team. Deebo Samuel is also in the spotlight, having requested a trade from the Niners, with the Broncos possibly being an ideal fit. Tyreek Hill's future remains uncertain, and he could potentially be available if the Dolphins field offers.

Quarterback Sam Darnold's return to the Vikings would solidify Justin Jefferson's elite status, while Aaron Rodgers is likely to find a new home, with speculation surrounding both the Steelers and Giants. Davante Adams is another intriguing name who may shift teams, targeting the Rams or Chargers, which could impact other receiving options on those rosters. Chris Godwin is recovering from injury but remains a key asset as he enters free agency. The draft class is worth watching too, particularly Ashton Jeanty, who after a stellar college season, could disrupt traditional rankings. Matthew Stafford’s status with the Rams is also in question, with trade whispers growing louder.

San Francisco 49ers rookie running back Isaac Guerendo is likely to miss the upcoming game against the Miami Dolphins due to a hamstring injury. This injury follows a series of setbacks for the team's running backs, including Christian McCaffrey and Jordan Mason, who are out for the season.

Head coach Kyle Shanahan did not disclose the injury during a previous conference call, but sources indicate Guerendo's status is dire. Patrick Taylor Jr. is expected to step in as the primary running back, with Israel Abanikanda and Ke'Shawn Vaughn as potential options.

San Francisco 49ers running back Isaac Guerendo is optimistic about playing in the upcoming Thursday Night Football game against the Los Angeles Rams, despite dealing with a sprained foot. Sources indicate that he feels good and is listed as questionable for the match.

If Guerendo cannot play, Patrick Taylor is expected to take over the running back duties, given his familiarity with the team. Israel Abanikanda is also in the mix but may not be a starting option if Guerendo is available.

Isaac Guerendo, running back for the San Francisco 49ers, appears unconcerned about the foot sprain he sustained during a recent game, indicating that it was a precautionary measure. He had been performing well as the team's lead back before the injury.

With a game against the Los Angeles Rams approaching on Thursday, the team will monitor his condition closely. If Guerendo cannot play, Patrick Taylor will likely step in, supported by newly signed Israel Abanikanda.

The San Francisco 49ers are facing a challenging season with injuries to key running backs Christian McCaffrey and Jordan Mason, both now on injured reserve. In their absence, rookie Isaac Guerendo is expected to step up significantly, showcasing his speed and strength.

With a solid performance so far, Guerendo is prepared to take on a heavy workload as the team's primary running back for the remainder of the season. The 49ers have also added depth by claiming Israel Abanikanda and promoting Patrick Taylor Jr. from the practice squad.