The San Francisco 49ers are facing a challenging season with injuries to key running backs Christian McCaffrey and Jordan Mason, both now on injured reserve. In their absence, rookie Isaac Guerendo is expected to step up significantly, showcasing his speed and strength.
With a solid performance so far, Guerendo is prepared to take on a heavy workload as the team's primary running back for the remainder of the season. The 49ers have also added depth by claiming Israel Abanikanda and promoting Patrick Taylor Jr. from the practice squad.