Jake Brendel, the center for the 49ers, made a friendly wager with former Iowa tight end George Kittle regarding the outcome of the UCLA-Iowa game. Brendel, a UCLA alum, celebrated the Bruins' victory, which added to Kittle's string of losses in Iowa-related bets this season.

Jake Brendel earned a 70.0 overall grade, with a 49.1 pass-blocking grade, and did not allow any pressures on his pass-blocking snaps. His performance contributed to the offensive line's overall effectiveness in protecting Purdy during the game.

Center Jake Brendel expressed his disappointment over Aiyuk's injury, emphasizing the impact of losing a key offensive weapon. He highlighted the need for the rest of the roster to step up and maintain productivity despite the setbacks caused by injuries to multiple players.

Jake Brendel is performing well on the 49ers' offensive line, boasting a pass block win rate of 95.5%, which places him among the top players at his position. His consistent performance contributes to the overall strong showing of the line, despite the struggles of Colton McKivitz, and is crucial for protecting quarterback Brock Purdy, especially with the absence of key offensive playmakers. Keeping the offensive line intact will be vital as the 49ers face a tough upcoming schedule.

Jake Brendel has struggled significantly at the start of the 2024 season, posting the worst pass-blocking grade in the NFL at 29.5. This poor performance follows a decline from a relatively solid 2022 season, where he recorded a pass-blocking grade of 71.9. Last year, Brendel's numbers worsened, allowing two sacks, three quarterback hits, and 29 pressures, marking all career-worst totals. Despite fans voicing concerns and searching for replacement options, he remains the starter, as head coach Chris Foerster believes he is still better than the limited backup choices available. The potential return of Jon Feliciano from injury could provide another option later in the season.