Isaac Yiadom was replaced by rookie Renardo Green in nickel situations, marking a shift in the 49ers' defensive strategy. This change has contributed to the team's improved ability to match up in man coverage, enhancing their overall defensive performance.

Isaac Yiadom of the San Francisco 49ers has an advanced coverage grade of 2.5, placing him in the 82.04 percentile among cornerbacks. This ranking reflects his performance through the first seven weeks of the season, indicating a solid level of effectiveness in coverage.

Isaac Yiadom stepped into a starting role for the 49ers in the absence of Charvarius Ward due to a knee injury. His presence in the lineup contributed to the team's defensive efforts against the Seahawks, as they managed to limit Metcalf's impact on the game. Yiadom's performance added depth to the secondary during a crucial matchup, showcasing the team's resilience in overcoming injuries.

Isaac Yiadom made a significant impact during the 49ers' game against the Arizona Cardinals by blocking a field goal attempt. He not only disrupted the play but also set up a 61-yard touchdown return by teammate Deommodore Lenoir, giving the 49ers a crucial lead at that moment. Despite this defensive highlight, the 49ers ultimately lost the game.

Isaac Yiadom struggled defensively, often targeted by Rams quarterback Matthew Stafford. He gave up several completions and was penalized for pass interference, including a costly 48-yard call that led to a Rams touchdown. His performance highlighted the 49ers' vulnerabilities in pass coverage during the game.