Jaylon Moore is set to start at left tackle in place of Trent Williams, who is sidelined with an ankle injury. As a fourth-year lineman, Moore will be tasked with protecting the quarterback and maintaining the offensive line's effectiveness against the Bills, especially in challenging snowy conditions. His performance will be crucial as the 49ers navigate their injury woes and aim to bolster their offensive output.

Jaylon Moore is positioned to start at left tackle if Trent Williams remains unavailable. During the preseason finale against the Raiders, he struggled, allowing a team-high three pressures, highlighting concerns about the offensive line's performance without Williams.

Jaylon Moore is expected to take over at left tackle in place of Trent Williams during the preseason. He has been handling left tackle duties while Williams was absent due to his holdout. With significant injuries to the 49ers' top three guards, Williams' return is crucial for addressing the team's offensive line issues. Moore has filled in during a challenging period but is anticipated to step aside once Williams resumes his starting role.

Jaylon Moore is listed as an extra tackle for the 49ers, providing depth behind the starting offensive line while All-Pro Trent Williams is holding out for a new contract.

Jaylon Moore is expected to serve as an extra tackle for the 49ers due to All-Pro Trent Williams holding out for a new contract. With this situation, Moore's role becomes crucial in providing depth on the offensive line.